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RESEARCH PAPER / 2026-06-10

DXA-derived regional adiposity identifies hidden liver-metabolic risk beyond BMI in non-obese older adults: a cross-sectional study.

Simone Perna, Giuseppe Mazzola, Eleonora Patta, Mariangela Rondanelli

Department of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, University of Milan, 20133 Milan, Italy. Electronic address: [email protected]. · pubmed

Abstract

In older adults, body mass index (BMI) may underestimate clinically relevant adiposity because aging is accompanied by loss of lean mass and preferential accumulation of visceral and ectopic fat. We examined whether DXA-derived visceral adipose tissue (VAT) identifies hidden liver-metabolic risk beyond BMI in non-obese older adults.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

DXA-derived visceral adipose tissue (VAT) can identify hidden liver-metabolic risk in non-obese older adults beyond what BMI indicates. This study addresses the underlying issue of adiposity and its implications for metabolic health in aging populations, which is crucial for understanding and potentially mitigating age-related diseases.

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