Guardian of two galaxies: Senescence-associated immune cells control disease tolerance and aging.

Wolfgang Vivas, Sebastian Weis

Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Jena, Germany; Institute of Infectious Diseases and Infection Control, Jena University Hospital, Friedrich Schiller University, Jena, Germany. Electronic address: [email protected] Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Jena, Germany; Institute of Infectious Diseases and Infection Control, Jena University Hospital, Friedrich Schiller University, Jena, Germany. Electronic address: [email protected]. · pubmed

Paper

Abstract

Preservation of host fitness is a common feature of longevity and immunity to infection. In this issue of Immunity, Triana-Martinez et al. reveal that p16

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Research summary

The paper claims that senescence-associated immune cells play a role in controlling disease tolerance and aging. This research is relevant as it explores mechanisms that could address the root causes of aging and improve longevity through immune system modulation.

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