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RESEARCH PAPER / 2026-06-04

Androgen therapy and musculoskeletal health in older adults: An umbrella review.

P P López Hilario, V R Gabiati Niedo, K S Khan, N Cano-Ibáñez

Departamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain.Departamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain. · pubmed

Abstract

Testosterone and androgen supplementation have been increasingly prescribed in older adults to counteract age-related declines in lean body mass and strength, however, there is uncertainty about their benefits. We synthesized the evidence concerning androgen therapy, particularly testosterone, on muscle-related outcomes in older adults.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that androgen therapy, particularly testosterone supplementation, may have effects on muscle-related outcomes in older adults. This research is relevant as it addresses potential interventions that could influence physical health and functional capacity in aging populations, which are critical factors in longevity.

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