Triangulating Evidence from Observational and Mendelian Randomization Studies of Leisure Screen Time for Epigenetic Age Acceleration.
Abstract
Sedentary behavior is associated with premature aging and mortality; however, its relationship with epigenetic age acceleration and the pathways mediating this association remain unclear. We applied a triangulation approach integrating observational and Mendelian randomization (MR) analyses to investigate these associations and identify potential mediators.
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Research summary
The paper investigates the relationship between leisure screen time and epigenetic age acceleration, suggesting that sedentary behavior may influence biological aging processes. This research is relevant as it explores potential mediators of aging-related outcomes, contributing to our understanding of lifestyle factors that may affect longevity.
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