EXPRESS: Meningeal CSF transport varies across parasagittal dura subregions with age in humans.

Vadim Malis, Hye Na Jung, Yoshiki Kuwatsuru, Won Bae, Mitsue Miyazaki

Department of Radiology, University of California San Diego, La Jolla, CA, USA.Department of Radiology, University of California San Diego, La Jolla, CA, USA. · pubmed

Paper

Abstract

Cerebrospinal fluid (CSF) transport along meningeal pathways contributes to brain fluid homeostasis and is thought to change with aging, yet quantitative, region-resolved measurements across lifespan remain limited. We hypothesized that meningeal CSF transport dynamics exhibit region-specific age associations rather than uniform decline.

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Research summary

Meningeal CSF transport dynamics exhibit region-specific age associations rather than a uniform decline. This research is relevant as it explores the mechanisms of cerebrospinal fluid transport in relation to aging, which could contribute to understanding the biological processes underlying age-related changes in brain function.

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