Universal transcriptomic hallmarks of mammalian ageing and mortality.

Alexander Tyshkovskiy, Daria Kholdina, Maria Davitadze, Adrian Molière, Alibek Moldakozhayev, Yoshiyasu Tongu, Tomoko Kasahara, Dmitrii Glubokov, Alec Eames, Leonid M Kats, Anastasiya Vladimirova, Kejun Ying, Hanna Liu, Bohan Zhang, Uma Khasanova, Mahdi Moqri, Jeremy M Van Raamsdonk, David E Harrison, Randy Strong, Takaaki Abe, Sergey E Dmitriev, Vadim N Gladyshev

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. [email protected]. · pubmed

Paper

Abstract

Ageing and interventions modulate health and mortality

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims to identify universal transcriptomic hallmarks of mammalian ageing and mortality. This research is relevant as it addresses the biological mechanisms underlying aging, which could lead to insights for lifespan extension and interventions targeting the root causes of age-related decline.

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