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RESEARCH PAPER / 2026-05-27

Exceptional parental longevity modifies the associations of kidney function and kidney aging with cardiovascular disease.

Laith Alzyood, Tina Gao, Sanish Sathyan, Sandra Aleksic, Sofiya Milman, Nir Barzilai, Michal L Melamed, Wei Chen

Department of Medicine/Division of Nephrology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, United States.Department of Medicine/Division of Nephrology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, United States. · pubmed

Abstract

Chronic kidney disease (CKD) is associated with cardiovascular disease (CVD). Exceptional parental longevity protects against CVD. We examined whether exceptional parental longevity modified the associations of kidney function and kidney aging with CVD in older adults.

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Research summary

Exceptional parental longevity modifies the associations of kidney function and kidney aging with cardiovascular disease in older adults. The study explores how exceptional longevity in parents may influence the relationship between kidney health and cardiovascular outcomes, which is pertinent to understanding factors that contribute to aging and longevity.

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