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RESEARCH PAPER / 2026-05-26

Electrical stimulation promotes longevity and regeneration in a colonial chordate.

Jos Domen, Yotam Voskoboynik, Tom Levy, Erica M Domen, Katherine J Ishizuka, Karla J Palmeri, Chiara Anselmi, Thomas Rolander, Norma F Neff, Angela M Detweiler, Irving L Weissman, Kimberly L Gandy, Debashis Sahoo, Ayelet Voskoboynik

Biology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950.Biology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950. · pubmed

Abstract

Endogenous bioelectric currents regulate development and regeneration, but their influence on organismal longevity and stem cell-mediated repair is not well understood. We demonstrate that a brief, clinically safe pulse of electrical current (PEC) produces lasting rejuvenation in the colonial chordate

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Research summary

A brief pulse of electrical current can induce lasting rejuvenation in a colonial chordate. This research explores a novel approach to influencing longevity and regeneration, addressing mechanisms that could potentially impact aging processes.

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