Superoxide-driven oxi-inflammatory activation in PBMC cultures: evidence supporting a cellular ageing trigger.

Ivana Beatrice Mânica da Cruz, Juliane Sasso, Marco Aurélio Echart Montano, Raquel de Souza Praia, Ivo Emílio da Cruz Jung, Maria Fernanda Mânica-Cattani, Cristina Maranghello, Railla da Silva Maia, Marcelo Araújo da Silva, Vitória Farina Azzolin, Francieli Bugiareki, Eduardo Velez-Martin, Ednea Aguiar Maia-Ribeiro, Euler Esteves Ribeiro, Verônica Farina Azzolin

Fundação Universidade Aberta da Terceira Idade, FUnATI, Manaus, Brazil. · pubmed

Paper

Abstract

Superoxide (O

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Research summary

The paper claims that superoxide-driven oxi-inflammatory activation in PBMC cultures serves as a trigger for cellular aging. This research addresses a potential root cause of aging through the investigation of oxidative stress and inflammation, which are key factors in the aging process.

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