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RESEARCH PAPER / 2026-05-23

Beta2-adrenergic receptor activation increases susceptibility to arrhythmogenesis in aging heart by impairing repolarization reserve via G

Sihao Zou, Yi Wang, Jia Chen, Li Yan, Lijie Gao, Kexin Li, Xianying Wang, Congxin Li

Department of Pharmacy, Hebei Medical University Third Hospital, No. 139 Ziqiang Road, Qiaoxi District, Shijiazhuang, 050051, Hebei, China.Department of Pharmacy, Hebei Medical University Third Hospital, No. 139 Ziqiang Road, Qiaoxi District, Shijiazhuang, 050051, Hebei, China. · pubmed

Abstract

In this study, age-related alterations in cardiac electrophysiology and the response to β

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that β2-adrenergic receptor activation increases susceptibility to arrhythmogenesis in the aging heart by impairing repolarization reserve. This research addresses age-related changes in cardiac function, which are critical for understanding the mechanisms of aging and potential interventions to improve heart health in older adults.

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