Impact of an online-guided physical activity intervention on cognition, resting-state brain connectivity, and the gut microbiome in healthy older adults-a randomized controlled trial.

Simon J Schrenk, Corinna Bang, Lena Best, Thomas Dost, Stefano Flor, Christiane Frahm, Christian Gaser, Rami Abou Hamdan, Marco Herbsleb, Christoph Kaleta, Fabian Kattlun, Hans-Josef Müller, Christian Puta, Monique Radscheidt, Adriana L Ruiz-Rizzo, André Scherag, Thomas Steidten, Otto W Witte, Stefan Brodoehl, Kathrin Finke

Department of Neurology, Jena University Hospital - Friedrich Schiller University of Jena, Am Klinikum 1, Jena, 07747, Germany. [email protected]. · pubmed

Paper

Abstract

Physical activity may enhance cognition in older adults, yet evidence from randomized controlled trials (RCTs) on mechanistic pathways remains inconclusive.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that an online-guided physical activity intervention can improve cognition, brain connectivity, and gut microbiome in healthy older adults. This research is relevant as it explores the potential of physical activity to address cognitive decline, which is a significant aspect of aging and longevity.

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