Postbiotic derived from Lacticaseibacillus paracasei CNCM I-5220 as a novel approach to improve ageing-induced skin damage.
Abstract
The ageing process impacts skin health by reducing cell turnover and altering skin microbiota, which plays a crucial role in maintaining homeostasis and protection against pathogens. Microbiota-derived metabolites, including postbiotics generated through nutrient fermentation, may contribute to these protective functions. In this context, topical application of postbiotics represents a promising strategy to mitigate visible signs of skin ageing. We investigated the effects of PB-SKF, a postbiotic derived from the fermentation of fructooligosaccharides (FOS) by Lacticaseibacillus paracasei strain CNCM I-5220
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Research summary
The paper claims that a postbiotic derived from Lacticaseibacillus paracasei can improve skin health by mitigating signs of aging. The research addresses a potential intervention for aging-related skin damage, which aligns with longevity research.
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