Targeting VAMPs in Aging-Related Diseases: From Mechanisms to Pharmacotherapy.

Binru Jia, Huidan Dong, Yu Liu, Xinru Liu, Xiaoning Zhu, Chengpeng Sun, Qiang Zhang, Ning Kang

School of Medical Technology, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China. · pubmed

Paper

Abstract

Vesicle-associated membrane proteins (VAMPs) are key regulators of membrane fusion, vesicular trafficking and intercellular communication. Structurally and functionally diverse, VAMPs participate in multiple physiological processes, and their dysfunction facilitates the progression of various aging-related diseases. This review aims to systematically summarize the molecular mechanisms and therapeutic potential of VAMPs.

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Research summary

The paper discusses the role of VAMPs in aging-related diseases and their potential therapeutic applications. The focus on VAMPs as regulators of cellular processes linked to aging suggests a connection to the underlying mechanisms of aging and age-related diseases.

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