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RESEARCH PAPER / 2026-05-20

A Systematic Review and Meta-analysis on the association between sarcopenia and cognitive impairment in middle-aged and older adults from Latin America.

Angel Gabriel Garrido-Dzib, Saliha Karina Hernández-Chávez, Héctor Rubio-Zapata, Gonzalo Jorquera, Ana Ligia Gutiérrez-Solis

Hospital Regional de Alta Especialidad de la Península de Yucatán del Instituto Mexicano del Seguro Social para el Bienestar, St. 7, No. 433 x 20 y 22, Fraccionamiento Altabrisa, Mérida, Yucatán 97130, Mexico; Facultad de Medicina, Universidad Autónoma de Yucatán (UADY), Avenida Itzaes No. 498 x 59 y 59A, Col. Centro, Mérida, Yucatán, Mexico. · pubmed

Abstract

Reduction in skeletal muscle mass, strength, and function, such as sarcopenia, have been associated with cognitive impairment. In Latin America (LATAM), evidence remains scarce, a critical gap given the region rapid demographic aging. Therefore, the present study aims to evaluate the association between sarcopenia and cognitive impairment among middle-aged and older adults in LATAM countries.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that there is an association between sarcopenia and cognitive impairment in middle-aged and older adults in Latin America. This research addresses a significant gap in understanding how physical decline may relate to cognitive health in aging populations, which is crucial for developing interventions that could improve longevity and quality of life.

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