METTL3 Regulates the Senescence of Stem Cells From the Apical Papilla by Mediating the m

Cheng Sun, Yuxin Fang, Zehan Li, Wuli Li

College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research, Hefei, Anhui, China.College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research, Hefei, Anhui, China. · pubmed

Paper

Abstract

We aimed to investigate whether N6-methyladenosine (m⁶A) methylation modification mediated by METTL3 regulates the senescence of SCAPs, and to elucidate the underlying molecular mechanisms.

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Research summary

The paper claims that METTL3-mediated m⁶A methylation regulates the senescence of stem cells from the apical papilla. This research is relevant as it explores the molecular mechanisms underlying cellular senescence, which is a key factor in aging and longevity.

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