A study on 18F-FDG PET/CT imaging assessment of the anti-aging efficacy of BMMSCs in the macaque brain.

Pinghui Li, Yaxi Jiang, Xinghua Pan, Xiangqing Zhu, Baoci Shan, Tingting Pan, Shici Yang, Qinghua Li, Ting Li, Jie Li, Lilin Chen, Rui He, Fei Xie, Gaohong Zhu

Department of Nuclear Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province 650032, China. · pubmed

Paper

Abstract

Aging is a pressing global challenge requiring urgent solutions, and the anti-aging potential of mesenchymal stem cells (MSCs) has drawn global attention. This study treated aged macaques with bone marrow mesenchymal stem cells (BMMSCs) and aimed to establish a non-invasive, reliable, specific, and reproducible imaging method for evaluating BMMSCs' therapeutic effects by combining 18F-FDG PET/CT imaging with texture analysis and Statistical Parametric Mapping 8.0 (SPM8.0).

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The study investigates the anti-aging efficacy of bone marrow mesenchymal stem cells (BMMSCs) in aged macaques using advanced imaging techniques. This research is relevant as it explores potential interventions targeting the aging process rather than merely addressing age-related diseases.

Author of this paper? Send a correction.