Berberine alleviates radiation-induced intestinal injury by inhibiting cellular senescence.

Xiaofeng Niu, Zheng Ren, Lijuan Deng, Siyu Yang, Jingyan Gao, Chengliu Bi, Ruolan Wang, Shaomei Sun, Ao Chen, Qinqing Li, Jun Yang

Department of Radiology, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, Kunming, China. · pubmed

Paper

Abstract

The aim was to study the inhibitory effect of berberine (BBR) on intestinal senescence induced by radiation and explore its mechanism.

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Research summary

Berberine inhibits cellular senescence induced by radiation, alleviating intestinal injury. The study addresses cellular senescence, a key mechanism in aging, suggesting potential implications for longevity and age-related tissue damage.

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