Testosterone and Bone Health in Men.

Hussein Kafel, Shehzad Basaria

Division of Endocrinology, Diabetes and Metabolism, Brigham and Women's Hospital, Research Program in Men's Health, Aging and Metabolism, Harvard Medical School, 221 Longwood Ave, BLI 541, Boston, MA, 02115, USA.Division of Endocrinology, Diabetes and Metabolism, Brigham and Women's Hospital, Research Program in Men's Health, Aging and Metabolism, Harvard Medical School, 221 Longwood Ave, BLI 541, Boston, MA, 02115, USA. · pubmed

Paper

Abstract

To elucidate the association between testosterone and skeletal health in men. In this review, i) we discuss the influence of testosterone on bone metabolism, ii) review population studies demonstrating the relationship between sex steroid concentrations and bone mineral density (BMD) and bone quality, and iii) summarize data from seminal trials of testosterone therapy and its effects on bone density and fracture risk.

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Research summary

Testosterone positively influences bone metabolism and density in men. The paper is relevant as it explores the role of testosterone in skeletal health, which is a critical aspect of aging and longevity.

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