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RESEARCH PAPER / 2026-05-06

Early Women's Health Research on Endurance Exercise Training and Cardiovascular Aging at the University of Colorado Boulder Using the Masters Athlete Model.

Douglas R Seals, Christopher A DeSouza, Hirofumi Tanaka, Kerrie L Moreau, Sanna Darvish, Charlie Ambrose, Kevin P Davy

Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO. · pubmed

Abstract

Because male physiology was historically viewed as the "norm" and data on females were considered difficult to interpret, little information regarding the effects of regular exercise on women's health over the lifespan was available leading into the 1990s. In 1993, we initiated research at the University of Colorado Boulder to determine the effects of endurance exercise training on healthy cardiovascular aging in women. To do so, we used a "masters athlete model" in which midlife and older female distance runners were compared with their healthy, but non-exercising peers, as well as young adult women. The masters runners (~50-70 years, mostly postmenopausal) had a maximal oxygen consumption (V̇O

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that endurance exercise training positively affects cardiovascular aging in women. This research is relevant as it addresses the impact of exercise on healthy aging and longevity in women, contributing to the understanding of lifestyle factors that can influence age-related health outcomes.

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