Spatiotemporally Responsive BEC Nanoplatform Targets Neutrophils to Reprogram Immune Crosstalk and Alleviate Periodontal Inflamm-Ageing in Periodontitis.

Jiaxin Luo, Jingxia Chen, Sicong Ren, Mucong Li, Shaobo Zhai, Sheng Chen, Jian Feng, Zhibo Wang, Hanchi Wang, Yanmin Zhou

Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun, China.Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun, China. · pubmed

Paper

Abstract

To investigate the underlying mechanism of immune cell crosstalk in periodontal inflammatory ageing and to explore potential pharmaceutical interventions for safely reversing this process.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims to explore pharmaceutical interventions that can reverse immune crosstalk related to periodontal inflammatory ageing. This research is relevant as it addresses mechanisms that may contribute to the aging process and seeks to mitigate age-related inflammation, which is a significant factor in longevity.

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