Association between the oxidative balance score and biological aging measured by epigenetic clock: insight from the NHANES 1999-2002.

Mingming Lv, Zhihui Jiang, Changjiang Deng, Zhiyan Du, Bingxin Bai, Zhilong Wang, Adilai Adilijiang, Ying-Ying Zheng, Xiang Xie

Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, People's Republic of China.Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, People's Republic of China. · pubmed

Paper

Abstract

Oxidative stress is a key factor leading to oxidative damage in cells and tissues, and is a major driving force behind aging and various age-related diseases. Epigenetic clock and oxidative balance score (OBS) serve as reliable indicators for assessing an individual's aging process and oxidative stress levels, respectively. However, no study has comprehensively assessed the association between epigenetic clock and OBS.

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Research summary

The paper claims that there is an association between the oxidative balance score and biological aging as measured by the epigenetic clock. This research is relevant as it explores the relationship between oxidative stress and biological aging, which are fundamental aspects of the aging process and potential targets for interventions in longevity.

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