Association between gut microbiota and sarcopenia in older adults: a cross-sectional analysis from the second wave of the Birjand Longitudinal Aging Study (BLAS).

Fatemeh Ramezani Kashal, Farshad Sharifi, Sadaf Najafi, Fateme Ettehad Marvasti, Mitra Moodi, Ebrahim Shafaei, MinaSadat Taghavi, Fatemeh-Sadat Hosseini, Masoumeh Khorashadizadeh, Mohammad Hasan Namaei, Ramin Heshmat, Gita Shafiee, Hanieh-Sadat Ejtahed

Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. · pubmed

Paper

Abstract

Investigating gut microbiota has emerged as a novel approach to exploring the gut-muscle axis and its link to age-related conditions like sarcopenia. While studies suggest gut dysbiosis may promote inflammation and muscle loss, findings vary by region and ethnicity. This study examined the association between gut microbiota and primary sarcopenia in an older adult population in Iran.

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Research summary

The paper claims that there is an association between gut microbiota and primary sarcopenia in older adults. This research is relevant as it explores the gut-muscle axis, which may provide insights into underlying mechanisms of age-related muscle loss, a significant aspect of aging.

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