The Influence of Accelerated Aging-Related Cardiac Remodeling on Cardiovascular Outcomes: an observational study.

Zhi Lv, Kexin Li, Chang Liu, Peiqi Liu, Zi Kou, Mingjuan Zhang, Dengfeng Gao

Department of Cardiology, The Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, West 5th Road, Xi'an, 710004, Shaanxi, China.Department of Cardiology, The Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, West 5th Road, Xi'an, 710004, Shaanxi, China. · pubmed

Paper

Abstract

This study aimed to investigate the associations between phenotypic age acceleration (PhenoAgeAccel) and different CVD outcomes and mortality, examine its relationship with cardiac structure and function using cardiac magnetic resonance imaging (CMR), and explore potential mediating pathways involving cardiac remodeling and cardiometabolic diseases.

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Research summary

The study investigates the relationship between phenotypic age acceleration and cardiovascular outcomes, emphasizing the role of cardiac remodeling in aging-related diseases. This research is relevant as it explores mechanisms associated with aging and their impact on cardiovascular health, which is a critical aspect of longevity research.

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