Microvascular health and frailty: nailfold capillaroscopy as a window into aging.

Arzu Nevin Dagdemir, Pinar Akyuz Dagli, Gulsah Soyturk, Rana Tuna Dogrul, Zeynep Sahiner, Cemile Peker, Hande Selvi Oztorun, Yuksel Maras, Sukran Erten, Gunes Eken, Kamile Silay

Department of Geriatrics, Bilkent City Hospital, Ankara, Turkey. [email protected] of Geriatrics, Bilkent City Hospital, Ankara, Turkey. [email protected]. · pubmed

Paper

Abstract

Frailty is a prevalent geriatric syndrome characterized by diminished physiological reserves and increased vulnerability to stressors. Microvascular dysfunction and inflammaging have been proposed as key biological mechanisms underlying frailty; however, objective and practical vascular biomarkers remain limited. Nailfold capillaroscopy (NFC), a non-invasive imaging method that visualizes microcirculatory architecture, may offer novel insight into the vascular component of frailty. This study aimed to investigate the association between frailty and NFC findings in older adults.

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Research summary

The paper investigates the association between frailty and nailfold capillaroscopy findings in older adults. This research is relevant as it explores microvascular health as a potential underlying mechanism of frailty, which is a significant aspect of aging and longevity.

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