Long-Term Consequences of Preterm birth: A Lifespan Perspective.
Abstract
Preterm birth is increasingly recognized as a determinant of health across the lifespan, influencing neurodevelopment, psychiatric risk, cardiovascular function, and mortality. This review synthesizes current evidence linking early-life adversity, including that associated with prematurity, to accelerated aging of to the brain-heart axis. We further describe the "fetus to fifty" model, highlighting how the early-life experiences of preterm-born infants impact adult trajectories across the lifespan.
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Research summary
Preterm birth has long-term consequences that affect health trajectories across the lifespan. The paper is relevant as it explores how early-life adversity, specifically prematurity, influences aging processes and health outcomes throughout life.
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