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RESEARCH PAPER / 2026-04-24

Natural senolytic activity of

Ryo Furuuchi, Yohko Yoshida, Goro Katsuumi, Takaaki Furihata, Yusuke Joki, Chieh-Lun Hsiao, Masayoshi Suda, Hana Saito, Tamano Kumazaki, Hidefumi Makabe, Manabu Abe, Ippei Shimizu, Tohru Minamino

Advanced Research Institutes, Bourbon Corporation, Niigata 956-0841, Japan. · pubmed

Abstract

The accumulation of senescent cells drives age-related diseases, and their removal (senolysis) has been reported to ameliorate pathological aging phenotypes. Here, we identified

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Research summary

The paper claims to identify natural senolytic activity that can remove senescent cells. This research addresses the root cause of aging by focusing on senolysis, which is directly related to ameliorating age-related diseases and potentially extending lifespan.

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