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RESEARCH PAPER / 2026-04-22

Sleep Regularity and Age-Related Eye Diseases: Prospective Analyses with Retinal Imaging and Multimorbidity Assessment in the UK Biobank.

Xuehao Cui, Jiajia Yuan, Qiuchen Zhao, Patrick Yu-Wai-Man, Tianyu Zheng

Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK.Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK. · pubmed

Abstract

Sleep regularity, a key circadian dimension of sleep health, has been linked to cardiometabolic and neurodegenerative outcomes, yet its relevance to ocular ageing remains unclear. The retina is a metabolically active, circadian-regulated neural tissue, suggesting that irregular sleep may contribute to the development of age-related eye diseases.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Irregular sleep may contribute to the development of age-related eye diseases. The paper explores a potential link between sleep regularity and ocular aging, addressing a factor that could influence the onset of age-related conditions, thus contributing to the understanding of aging processes.

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