Yunnan pickled tea partially mitigates d-galactose-induced aging in mice via Bacteroides vulgatus-associated microbiota-gut-liver-brain axis.

Guihua Xie, Zhipeng Liu, Fengmei Lu, Yanqun Fan, Zilong Wang, Zhifang Zhang, Shuwen Lei, Yi Zhang, Caiyou Lv, Yan Hou

College of Tea Science, Yunnan Agricultural University, Kunming, China.College of Tea Science, Yunnan Agricultural University, Kunming, China. · pubmed

Paper

Abstract

Aging is associated with chronic inflammation, oxidative stress, and metabolic disturbances. Pickled tea has been reported to demonstrate antioxidant and anti-inflammatory activity; however, its effects on aging and the related mechanisms remain unclear. This study investigated whether Yunnan pickled tea could attenuate d-galactose-induced aging in Kunming mice. It explored the potential involvement of the microbiota-gut-liver-brain axis.

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Research summary

Yunnan pickled tea can mitigate aging effects induced by d-galactose in mice through the microbiota-gut-liver-brain axis. The study addresses potential mechanisms related to aging and explores a natural intervention, which aligns with longevity research.

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