Decline in cardiorespiratory fitness and its association with vascular aging and subclinical atherosclerosis in healthy older adults: a 3-year longitudinal study.

Vincent Groesser, Christopher Weyh, Torsten Frech, Natascha Sommer, Klaus Eder, Astrid Most, Samuel Sossalla, Karsten Krüger, Pascal Bauer

Department of Cardiology and Angiology, Justus-Liebig-University Giessen, 35390, Giessen, Germany. [email protected] of Cardiology and Angiology, Justus-Liebig-University Giessen, 35390, Giessen, Germany. [email protected]. · pubmed

Paper

Abstract

Aging is associated with progressive deterioration of vascular function and cardiovascular risk. Cardiorespiratory fitness (CRF) is closely associated with cardiovascular health, yet longitudinal data in healthy older adults remain limited. This study examined 3-year changes in vascular and echocardiographic parameters in older adults and their associations with CRF and muscle strength. Forty-nine participants (mean age 63.8 ± 3.8 years) underwent vascular assessments (brachial/central blood pressure (BP), pulse wave velocity (PWV), augmentation index), echocardiography, CRF testing via spiroergometry to determine VO

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Research summary

The study claims that declines in cardiorespiratory fitness are associated with vascular aging and subclinical atherosclerosis in healthy older adults. This research is relevant as it explores the relationship between physical fitness and cardiovascular health, which are critical factors in the aging process and longevity.

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