Gut Microbiota-Linked Benefits of Low-Intensity Pulsed Ultrasound Rejuvenate the Ageing Muscle.

Jia-Hua Jhuang, Kuo-Cheng Lan, Ting-Yu Chang, Ding-Cheng Chan, Shing-Hwa Liu

Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan.Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan. · pubmed

Paper

Abstract

Ageing is an inevitable biological process that contributes to increased prevalence of age-associated diseases, including sarcopenia, defined by progressive loss of muscle mass, functional decline and a heightened risk of injury. Developing effective interventions remains a critical clinical priority. This study employed a natural ageing mouse model to investigate whether noninvasive low-intensity pulsed ultrasound (LIPUS), a therapeutic ultrasound, delivered to the abdomen, could alleviate age-related muscle deterioration and whether its effects were linked to gut microbiota modulation.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that low-intensity pulsed ultrasound can rejuvenate aging muscle through gut microbiota modulation. This research is relevant as it explores a potential intervention targeting the underlying mechanisms of aging and muscle deterioration, rather than merely addressing symptoms.

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