Exercise rejuvenates bone marrow mesenchymal stem cells associated with the inhibition of inflammatory factors and senescence-related factors.

Xiu-Juan Dong, Qi Zhao, Wei-Min Zhang, Jian-Gang Liu, Xin-Ding Zhang, Rong Yi

College of Physical Education, Hainan Normal University, 570100, China.College of Physical Education, Hainan Normal University, 570100, China. · pubmed

Paper

Abstract

To investigate the effects of exercise on bone marrow stem cells (BMSCs) and determine underlying molecular network mechanisms through bioinformatics analysis combined experimental validation.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Exercise positively influences bone marrow mesenchymal stem cells by inhibiting inflammatory and senescence-related factors. This research addresses the underlying mechanisms of aging by exploring how exercise can rejuvenate stem cells, which is directly related to longevity and age-related cellular decline.

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