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RESEARCH PAPER / 2026-04-17

Reconstructing mammalian lifespan evolution reveals strong phylogenetic effects and lifespan-associated genes.

Zhen-Na Zhang, Xue Lyu, Shan-Zhuang Niu, Dong-Ming Xu, Cheng-Gang Zou

State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming, China.State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming, China. · pubmed

Abstract

Despite the extraordinary diversity in mammalian lifespans, the evolutionary trajectories and underlying molecular mechanisms governing this variation remain largely uncharacterized.

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Research summary

The paper claims to identify evolutionary trajectories and molecular mechanisms associated with mammalian lifespan variation. This research is relevant as it explores the evolutionary basis of lifespan, which could provide insights into the biological mechanisms of aging and potential interventions for lifespan extension.

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