Replication of the Association between Retinal Aging Clock Susceptibility Genes and Retinal Age Gap in an Asian Population: The Nagahama Study.

Yoshifumi Komatsu, Takuro Kamei, Kazuya Morino, Shin-Ya Nakao, Masahiro Akada, Keina Sado, Yuta Doi, Tomotaro Tanaka, Masayuki Hata, Yasuharu Tabara, Fumihiko Matsuda, Akitaka Tsujikawa, Masahiro Miyake

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan. · pubmed

Paper

Abstract

To replicate previously reported genetic associations for the retinal aging clock-quantified as the retinal age gap-in an East Asian population and to assess cross-ancestry consistency of effect directions and sizes.

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Research summary

The paper claims to replicate genetic associations related to retinal aging in an East Asian population. The study is relevant as it investigates genetic factors that may contribute to the biological processes of aging, specifically in the context of retinal aging, which could have implications for understanding longevity and age-related diseases.

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