Effects of high-load, velocity-intentional variable resistance training combined with creatine supplementation on neuroplasticity, oxidative stress, inflammation, physical function, cognitive performance and quality of life in older adults: A randomized, double-blind, placebo-controlled trial.

Julio Fernandez-Garrido, Ezequiel G Martin, Angel Saez-Berlanga, Pedro Gargallo-Bayo, Javier Gene-Morales, Carlos Alix-Fages, Pablo Jiménez-Martínez, Oscar Caballero, Rosario Salvador-Palmer, Juan C Colado

Nursing Department, Faculty of Nursing and Podiatry, University of Valencia, Valencia, Spain. Electronic address: [email protected]. · pubmed

Paper

Abstract

To compare two 16-week high-load, velocity-intentional resistance training programs-elastic bands (HL-VIRT-EB) vs. water-based (HL-VIRT-AQ)-combined with creatine or placebo supplementation on neuroplasticity, oxidative stress, inflammation, strength, physical function, cognition, and quality of life in older adults.

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Research summary

The paper claims that high-load, velocity-intentional resistance training combined with creatine supplementation can improve neuroplasticity, oxidative stress, inflammation, physical function, cognitive performance, and quality of life in older adults. This research addresses factors that contribute to aging and aims to enhance physical and cognitive health in older adults, which is relevant to longevity.

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