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RESEARCH PAPER / 2026-04-02

Automated CT-Based Muscle Density Predicts Mortality Regardless of Muscle Area.

Adam J Kuchnia, Glen M Blake, Matthew H Lee, Jevin Lortie, Rachel Fenske, John W Garrett, Perry J Pickhardt

Department of Nutritional Sciences, University of Wisconsin, Madison, Wisconsin, USA.Department of Nutritional Sciences, University of Wisconsin, Madison, Wisconsin, USA. · pubmed

Abstract

Abdominal CT-based assessments of skeletal muscle may provide important prognostic information for all-cause mortality in aging adults. We aimed to evaluate whether AI-segmented muscle area and muscle density predict long-term survival in a large, retrospective adult population.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Automated CT-based assessments of muscle density can predict mortality in aging adults. The study addresses a potential biomarker related to aging and longevity, focusing on muscle health as a critical factor in overall survival.

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