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RESEARCH PAPER / 2026-03-30

Cross-sectional evaluation of cardiovascular biological age using point-of-care ultrasound.

Roi Amster, Abigail Goshen, Harel Raanani, Adiel Am-Shalom, Michael Fiman, Robert Klempfner, Ehud Raanani, Ehud Schwammenthal, Evelyne Bischof, Elad Maor, Tzipora Strauss

Sheba Longevity Center, Sheba Medical Center, Ramat Gan, Israel.Sheba Longevity Center, Sheba Medical Center, Ramat Gan, Israel. · pubmed

Abstract

Biological age is increasingly recognized as a superior predictor of morbidity, mortality, compared with chronological age. Artificial intelligence (AI)-driven ageing clocks enable rapid, non-invasive assessment. Cardiovascular (CV) ageing is of particular relevance given its central role in systemic metabolic health. This study evaluated the clinical utility of an ultrasound (US)-based CV biological age clock derived from handheld point-of-care ultrasound (POCUS), in comparison with haematological and electrocardiographic (ECG)-based clocks.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The study claims that a point-of-care ultrasound-based cardiovascular biological age clock can provide a rapid, non-invasive assessment of biological age. This paper is relevant as it explores a novel approach to assessing biological age, which is a key factor in understanding and potentially mitigating age-related diseases and improving longevity.

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