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RESEARCH PAPER / 2026-03-26

Cellular senescence in neurodegenerative diseases: A bibliometric analysis and mechanistic synthesis linking translational pathways to therapeutic implications.

Runjin Zhou, Xiaoling Lin, Jian Lin, Zhenge Liao, Haojie Ni, Xingdong Lin, Qiuxing He, Weimin Ning

Dongguan Hospital of Guangzhou University of Chinese Medicine, Dongguan, China; Medical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, China; Guangzhou University of Chinese Medicine, Guangzhou, China. · pubmed

Abstract

Cellular senescence is now recognized as a pivotal driver of neurodegenerative diseases (NDs). Despite advances in understanding senescence mechanisms, such as the p16

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that cellular senescence is a key driver of neurodegenerative diseases and explores translational pathways for therapeutic implications. This research is relevant as it addresses the underlying mechanisms of aging-related diseases, potentially leading to interventions that target the root causes of neurodegeneration.

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