Association of leukocyte mitochondrial DNA copy number and inflammation with mortality among older adults.

I-Chien Wu, Chin-San Liu, Wen-Ling Cheng, Ta-Tsung Lin, Pei-Fen Chen

Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan. [email protected]. · pubmed

Paper

Abstract

As the population ages, a rising mortality burden is attributed to deaths in older adults, particularly deaths from inflammation-related chronic non-communicable diseases. The synergism between aging and inflammation remains unclear. Here, we conducted a study to examine whether a decrease in leukocyte mitochondrial DNA copy number (mtDNA

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that a decrease in leukocyte mitochondrial DNA copy number is associated with increased mortality among older adults due to inflammation. This research is relevant as it explores the relationship between mitochondrial function, inflammation, and aging, which are critical factors in understanding the biological mechanisms of aging and longevity.

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