Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial.
Abstract
Age-associated sarcopenia and declining physical function in older women are connected to changes in hormones, inflammation, and disrupted protein metabolism. Myokines and cytokines play central roles in muscle atrophy. While both resistance exercise (RE) and essential amino acid (EAA) supplementation are promising interventions, limited randomized trials have assessed their combined effect in healthy elderly populations. Early targeted strategies may help delay sarcopenia and promote healthier aging.
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Research summary
Combined resistance exercise and essential amino acid intake enhance the follistatin/myostatin ratio and muscle fitness in older women. The paper addresses interventions that may help delay sarcopenia, which is a significant aspect of aging and contributes to overall longevity and health in older populations.
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