Agarose oligosaccharides balance intestinal stem cell homeostasis in aging D. melanogaster by regulating the Acetobacter persici-acetic acid-JAK/STAT signaling axis.

Shuhang Fan, Qiyu Xu, Qianyi Zhang, Jiayi She, Cheng Zhang, Mark Christian, Zhenyu Wang, Xianjun Dai

College of Life Sciences, China Jiliang University, Hangzhou, 310018, China.College of Life Sciences, China Jiliang University, Hangzhou, 310018, China. · pubmed

Paper

Abstract

Intestinal aging manifests as the decline in gut function and structure, affecting nutrient absorption and overall health. Agarose oligosaccharides (AOS) exhibit considerable anti-aging effects, but their mechanism of action remains unclear.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Agarose oligosaccharides promote intestinal stem cell homeostasis in aging D. melanogaster by modulating the JAK/STAT signaling pathway. This research addresses a mechanism related to aging and gut health, which is crucial for understanding the biological processes underlying longevity.

Author of this paper? Send a correction.