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RESEARCH PAPER / 2026-02-27

Intrinsic capacity and its dynamic change associate with risk of cardiovascular disease: Evidence from multinational prospective cohorts.

Yanzhi Liu, Jinxi Wang, Xuemei Zhao, Xinqing Li, Chengyi Wang, Jiaying Yang, Huiqiao Han, Qiong Zhou, Yuhui Zhang

Heart Failure Center, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.Heart Failure Center, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. · pubmed

Abstract

Cardiovascular disease (CVD) is the leading cause of mortality and disability in aging populations. Intrinsic capacity (IC) is a novel measure related to health outcomes. However, most previous studies focused on baseline IC within individual cohorts. We investigated IC and its longitudinal changes in relation to CVD across three prospective cohorts.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that changes in intrinsic capacity are associated with the risk of cardiovascular disease. This research is relevant as it explores a novel measure (intrinsic capacity) in relation to cardiovascular disease, which is a significant concern in aging populations, potentially contributing to our understanding of age-related health outcomes.

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