Mapping the scientific landscape of mitochondria-associated membranes: a bibliometric insight into emerging frontiers in aging and diseases.

Jiao Pang, Yunxiang Zhang, Yuan Tian, Xingrui Cao, Xueshu Tao, Cheng Sun, Zhipeng Cao

Department of Biology, College of Life Science, Northwest University, Xi'an City, Shannxi Province, P. R. China.Department of Biology, College of Life Science, Northwest University, Xi'an City, Shannxi Province, P. R. China. · pubmed

Paper

Abstract

Mitochondria-associated membranes (MAMs) are critical hubs coordinating energy metabolism, lipid homeostasis, and Ca2⁺ signaling, thereby regulating cell survival, stress responses, and apoptosis. Increasing evidence links MAMs dysfunction to aging, neurodegenerative diseases, metabolic disorders, and cancer. Although numerous mechanistic studies and narrative reviews have been published, a systematic, mechanism-oriented bibliometric evaluation of the global MAMs research landscape is still lacking.

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Research summary

The paper claims to provide a bibliometric evaluation of the research landscape surrounding mitochondria-associated membranes (MAMs) in relation to aging and diseases. The focus on MAMs dysfunction and its connection to aging processes aligns with the investigation of root causes of aging and age-related diseases.

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