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RESEARCH PAPER / 2026-02-23

Exploring age-related changes in bone and muscle: Insights from radiomics and MRI.

Maryam Elikaei Moghadam, Elmira Yazdani, Mohammad Bagher Shiran, Shahrokh Abbasi-Rad, Hamidreza Saligheh Rad, Malakeh Malekzadeh

Medical Physics Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address: [email protected] Physics Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address: [email protected]. · pubmed

Abstract

Age-related changes in muscle and bone can adversely affect musculoskeletal health. Current techniques often fail to capture subtle age-related changes in bone micro-architecture and muscle tissue. Magnetic resonance imaging (MRI) is a robust tool for analyzing age-related bone deterioration, while radiomics effectively captures subtle changes in muscle tissue by extracting intricate features.

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Research summary

The paper claims that MRI and radiomics can effectively capture subtle age-related changes in bone and muscle. This research is relevant as it addresses the underlying changes in musculoskeletal health associated with aging, which are critical for understanding and potentially mitigating age-related decline.

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