Wharton's jelly mesenchymal stem cell-secretome enhances skin rejuvenation via ApoA4 and SERPINH1.
Abstract
Skin aging arises from intrinsic processes and extrinsic insults (e.g., ultraviolet exposure and oxidative stress). Mesenchymal stromal cell (MSC)-derived secretome offers a cell-free approach to skin regeneration. Wharton's jelly-derived MSCs (WJ-MSCs) may outperform adipose-derived (AD-MSCs) and bone marrow-derived MSCs (BM-MSCs).
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Research summary
The paper claims that Wharton's jelly mesenchymal stem cell-secretome enhances skin rejuvenation through specific proteins. The research addresses skin aging, which is a fundamental aspect of the aging process and seeks to explore mechanisms that could potentially mitigate age-related skin degeneration.
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