Old Friends, New Faces in Endothelial Dysfunction and Senescence.

Niloofar Ale-Agha, Philipp Jakobs, Anne Rafflenbeul, Wiebke M Meyer, Simone Prömel, Judith Haendeler, Joachim Altschmied

Haendeler Group, Cardiovascular Degeneration, Central Institute of Clinical Chemistry and Laboratory Medicine, Medical Faculty, University Hospital and Heinrich Heine University of Düsseldorf, Düsseldorf, Germany.Haendeler Group, Cardiovascular Degeneration, Central Institute of Clinical Chemistry and Laboratory Medicine, Medical Faculty, University Hospital and Heinrich Heine University of Düsseldorf, Düsseldorf, Germany. · pubmed

Paper

Abstract

Onset and progression of cardiovascular diseases are tightly linked to the aging process. Aging results in structural and functional changes including endothelial dysfunction and senescence, thereby impairing vascular functions. The molecules involved in these processes are far from understood.

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Research summary

The paper claims that understanding the molecules involved in endothelial dysfunction and senescence is crucial for addressing cardiovascular diseases linked to aging. This research is relevant as it explores mechanisms underlying aging processes that contribute to age-related diseases, rather than merely addressing symptoms.

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