Abstract
Aging is frequently accompanied by inflammaging-a chronic, low-grade inflammatory state that contributes to functional decline and disease risk. Disruption of the intestinal barrier is increasingly being recognized as a key driver of inflammaging; however, its relationship with the gut microbiota in older adults remains poorly understood. Here, we demonstrate a significant association of intestinal barrier dysfunction markers with systemic inflammatory markers using a cross-sectional study in this population. Notably, the genus
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Research summary
The paper demonstrates a significant association between intestinal barrier dysfunction markers and systemic inflammatory markers in older adults. This research is relevant as it explores the underlying mechanisms of inflammaging, which is a key factor in aging and age-related diseases.
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