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RESEARCH PAPER / 2026-02-10

Biotechnological advances in key regulatory genes of phenylpropanoid and terpenoid biosynthesis pathways in Panax ginseng: Current insights and future prospects.

Mengyang Zhang, Jia Wu, Jie Zhang, Fu Wang, Youcheng Wang, Xiujuan Lei, Yingping Wang, Jian Zhang

College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, Jilin 130118, China; National & Local Joint Engineering Research Centre for Ginseng Breeding and Development, Changchun, Jilin 130118, China.College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, Jilin 130118, China; National & Local Joint Engineering Research Centre for Ginseng Breeding and Development, Changchun, Jilin 130118, China. · pubmed

Abstract

Panax ginseng, is one of the most important medicinal herbs, widely recognized for its therapeutic value in traditional and modern medicine. Its diverse pharmacological activities are primarily mediated by secondary metabolites, notably flavonoids and polyphenols from the phenylpropanoid pathway and ginsenosides from the terpenoid pathway, which exert strong antioxidant, anti-aging, and anti-inflammatory effects.

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Research summary

The paper discusses the biotechnological advances in regulatory genes of biosynthesis pathways that produce metabolites with anti-aging effects. The research is relevant as it explores the potential of these metabolites to address mechanisms associated with aging and longevity.

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