Supplementation with Lycium barbarum glycopeptide (LbGP) rescues the quality of aged oocytes.

Aolei Guo, Ruixin Shi, Sipei Liu, Yang Zhang, Yan Mao, Guijun Yan, Guangyi Cao

State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine and Obstetrics and Gynecology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, 210008, China. · pubmed

Paper

Abstract

Lycium barbarum L. (goji berry), a traditional medicinal and edible herb, has long been employed for its anti-aging, vision-enhancing, and anti-inflammatory properties. Lycium barbarum glycopeptide (LbGP), a major bioactive glycoconjugate isolated from this plant, possesses documented antioxidant and immunomodulatory activities. However, its specific therapeutic efficacy in counteracting reproductive aging and the precise mechanisms underlying its protective effects on oocyte quality remain to be fully elucidated.

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Research summary

Supplementation with Lycium barbarum glycopeptide (LbGP) improves the quality of aged oocytes. The paper addresses reproductive aging, which is a significant aspect of the aging process, potentially contributing to understanding and mitigating age-related decline in fertility.

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