Age-related redistribution of zinc and copper within human skin.

Nishat Zakaria, Alexander Griffiths, Clarisse Ganier, Magnus Lynch, David Messenger, Ranjit Bhogal, Wolfgang Maret

Department of Nutritional Sciences, Faculty of Life Sciences & Medicine, King's College London, UK.Department of Nutritional Sciences, Faculty of Life Sciences & Medicine, King's College London, UK. · pubmed

Paper

Abstract

The skin's natural functions rely on essential metals such as zinc and copper, which contribute to cell growth, differentiation, and apoptosis. With ageing, low-grade inflammation (inflammaging) develops, and zinc deficiency in skin becomes more common. Data on the distribution of these metals in human skin are limited and there is no information on how the distribution changes with age.

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Research summary

The paper claims that age-related changes in the distribution of zinc and copper in human skin contribute to low-grade inflammation and zinc deficiency. This research is relevant as it explores the underlying biochemical changes associated with aging, which could inform strategies for addressing age-related skin conditions and overall longevity.

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