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RESEARCH PAPER / 2026-02-06

The association of serum levels of vitamin D with leucocyte telomere length, as a marker of biological aging: A meta-analysis.

Jie Shen, Lin Wang, Jiyuan Liu, Zhichao Fan, Guanghui Li

Hebi Vocational and Technical College, Hebi, China.Hebi Vocational and Technical College, Hebi, China. · pubmed

Abstract

Short telomere length (TL) has been associated with chronic diseases and reduced lifespan. Vitamin D may help preserve telomeres through its anti-inflammatory effects; however, the relationship between serum 25-hydroxyvitamin D (25(OH)D) levels and TL remains inconclusive. This meta-analysis was conducted to evaluate the association between circulating 25(OH)D and leukocyte TL (LTL).

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that there is an association between serum levels of vitamin D and leukocyte telomere length. This research is relevant as it explores a potential biological mechanism (telomere length) that could influence aging and longevity, rather than merely addressing age-related diseases.

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